aptamer screening service-Aptamer Development

Nucleic acid aptamers are short, single-stranded oligonucleotides (ssDNA or ssRNA) capable of binding with high affinity and specificity to diverse targets, ranging from small molecules and proteins to entire cells. Due to their versatility and stability, aptamers have become invaluable tools in both basic research and clinical applications. The standard method for aptamer identification is Systematic Evolution of Ligands by Exponential Enrichment (SELEX), an iterative process involving repeated cycles of incubation, separation, elution, amplification, and single-strand purification, followed by sequencing.

At KMDbioscience, we have established a proprietary and highly optimized platform for efficient and reliable aptamer screening. Our services cover aptamer development against both purified protein targets and small chemical molecules. Through our refined selection process, we consistently generate DNA aptamers with dissociation constants (Kd) in the range of 0.1–10 nM. Typically, multiple unique aptamer sequences can be identified through successive selection rounds. Depending on client needs, we can provide the full panel of candidate aptamers obtained from the screening campaign.

Choose KMDbioscience as your partner to accelerate and enhance your aptamer-based projects. Let us help you advance your research and development goals with precision and expertise.

Aptamer Screening Service | Aptamer Development